The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins

The endoplasmic reticulum (ER) supports biosynthesis of proteins with diverse transmembrane domain (TMD) lengths and hydrophobicity. Features in transmembrane domains such as charged residues in ion channels are often functionally important, but could pose a challenge during cotranslational membrane...

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Detalhes bibliográficos
Publicado no:eLife
Principais autores: Shurtleff, Matthew J, Itzhak, Daniel N, Hussmann, Jeffrey A, Schirle Oakdale, Nicole T, Costa, Elizabeth A, Jonikas, Martin, Weibezahn, Jimena, Popova, Katerina D, Jan, Calvin H, Sinitcyn, Pavel, Vembar, Shruthi S, Hernandez, Hilda, Cox, Jürgen, Burlingame, Alma L, Brodsky, Jeffrey L, Frost, Adam, Borner, Georg HH, Weissman, Jonathan S
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995541/
https://ncbi.nlm.nih.gov/pubmed/29809151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37018
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