Cotranslational Biogenesis of Membrane Proteins in Bacteria

Nascent polypeptides emerging from the ribosome during translation are rapidly scanned and processed by ribosome-associated protein biogenesis factors (RPBs). RPBs cleave the N-terminal formyl and methionine groups, assist cotranslational protein folding, and sort the proteins according to their cel...

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Bibliografiske detaljer
Main Authors: Evan Mercier, Xiaolin Wang, Lena A. K. Bögeholz, Wolfgang Wintermeyer, Marina V. Rodnina
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-04-01
Serier:Frontiers in Molecular Biosciences
Fag:
N-terminal processing
membrane targeting
membrane insertion
membrane protein topology
translocon
cotranslational folding
Online adgang:https://www.frontiersin.org/articles/10.3389/fmolb.2022.871121/full
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