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Lateral gate dynamics of the bacterial translocon during cotranslational membrane protein insertion

During synthesis of membrane proteins, transmembrane segments (TMs) of nascent proteins emerging from the ribosome are inserted into the central pore of the translocon (SecYEG in bacteria) and access the phospholipid bilayer through the open lateral gate formed of two helices of SecY. Here we use si...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Mercier, Evan, Wang, Xiaolin, Maiti, Manisankar, Wintermeyer, Wolfgang, Rodnina, Marina V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256087/
https://ncbi.nlm.nih.gov/pubmed/34162707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2100474118
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