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DNA supercoiling measurement in bacteria

DNA supercoiling plays critical roles in several essential DNA metabolic pathways, such as replication, transcription and recombination. Typically plasmid DNA molecules are used to measure DNA supercoiling status inside bacterial cells. In this chapter, we describe how to isolate plasmid DNA molecul...

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Bibliographic Details
Published in:Methods Mol Biol
Main Authors: Liu, Yingting, Hua, Zhi-Chun, Leng, Fenfei
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995477/
https://ncbi.nlm.nih.gov/pubmed/29177733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7459-7_4
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