Epigenetic dysregulation of TET2 in human glioblastoma

Ten-eleven translocation (TET) enzymes are frequently deregulated in cancer, but the underlying molecular mechanisms are still poorly understood. Here we report that TET2 shows frequent epigenetic alterations in human glioblastoma including DNA hypermethylation and hypo-hydroxymethylation, as well a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: García, María G., Carella, Antonella, Urdinguio, Rocío G., Bayón, Gustavo F., Lopez, Virginia, Tejedor, Juan Ramón, Sierra, Marta I., García-Toraño, Estela, Santamarina, Pablo, Perez, Raúl F., Mangas, Cristina, Astudillo, Aurora, Corte-Torres, M. Daniela, Sáenz-de-Santa-María, Inés, Chiara, María-Dolores, Fernández, Agustín F., Fraga, Mario F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995234/
https://ncbi.nlm.nih.gov/pubmed/29899831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25406
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi