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Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes

BACKGROUND: Early life is a period of drastic epigenetic remodeling in which the epigenome is especially sensitive to extrinsic and intrinsic influence. However, the epigenome-wide dynamics of the DNA methylation changes that occur during this period have not been sufficiently characterized in longi...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Pérez, Raúl F., Santamarina, Pablo, Tejedor, Juan Ramón, Urdinguio, Rocío G., Álvarez-Pitti, Julio, Redon, Pau, Fernández, Agustín F., Fraga, Mario F., Lurbe, Empar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327427/
https://ncbi.nlm.nih.gov/pubmed/30626398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1751-9
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