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Dysregulation of the TET family of epigenetic regulators in lymphoid and myeloid malignancies

DNA methylation has pivotal regulatory roles in mammalian development, retrotransposon silencing, genomic imprinting, X-chromosome inactivation, and cancer. Cancer cells display highly dysregulated DNA methylation profiles, characterized by global hypomethylation in conjunction with hypermethylation...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Lio, Chan-Wang J., Yuita, Hiroshi, Rao, Anjana
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839946/
https://ncbi.nlm.nih.gov/pubmed/31467060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019791475
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