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Dysregulation of the TET family of epigenetic regulators in lymphoid and myeloid malignancies
DNA methylation has pivotal regulatory roles in mammalian development, retrotransposon silencing, genomic imprinting, X-chromosome inactivation, and cancer. Cancer cells display highly dysregulated DNA methylation profiles, characterized by global hypomethylation in conjunction with hypermethylation...
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| Vydáno v: | Blood |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6839946/ https://ncbi.nlm.nih.gov/pubmed/31467060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019791475 |
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