Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress

Posttranslational modifications of DNA repair proteins have been linked to their function. However, it is not clear if posttranslational acetylation affects subcellular localization of these enzymes. Here, we show that the human DNA glycosylase NEIL1, which is involved in repair of both endo- and ex...

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Publicat a:DNA Repair (Amst)
Autors principals: Sengupta, Shiladitya, Yang, Chunying, Hegde, Muralidhar L., Hegde, Pavana M., Mitra, Joy, Pandey, Arvind, Dutta, Arijit, Datarwala, Abdul Tayyeb, Bhakat, Kishor K., Mitra, Sankar
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992913/
https://ncbi.nlm.nih.gov/pubmed/29698889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.04.001
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