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Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress

Posttranslational modifications of DNA repair proteins have been linked to their function. However, it is not clear if posttranslational acetylation affects subcellular localization of these enzymes. Here, we show that the human DNA glycosylase NEIL1, which is involved in repair of both endo- and ex...

詳細記述

保存先:
書誌詳細
出版年:DNA Repair (Amst)
主要な著者: Sengupta, Shiladitya, Yang, Chunying, Hegde, Muralidhar L., Hegde, Pavana M., Mitra, Joy, Pandey, Arvind, Dutta, Arijit, Datarwala, Abdul Tayyeb, Bhakat, Kishor K., Mitra, Sankar
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992913/
https://ncbi.nlm.nih.gov/pubmed/29698889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.04.001
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