Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension

Background: Pulmonary hypertension (PH) is a devastating and progressive disease characterized by excessive proliferation of pulmonary artery smooth muscle cells (PASMCs) and remodeling of the lung vasculature. Adenosine signaling through the ADORA2B receptor has previously been implicated in diseas...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Physiol
Egile Nagusiak: Mertens, Tinne C. J., Hanmandlu, Ankit, Tu, Ly, Phan, Carole, Collum, Scott D., Chen, Ning-Yuan, Weng, Tingting, Davies, Jonathan, Liu, Chen, Eltzschig, Holger K., Jyothula, Soma S. K., Rajagopal, Keshava, Xia, Yang, Guha, Ashrith, Bruckner, Brian A., Blackburn, Michael R., Guignabert, Christophe, Karmouty-Quintana, Harry
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2018
Gaiak:
Physiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992271/
https://ncbi.nlm.nih.gov/pubmed/29910735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00555
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