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Collagen abundance controls melanoma phenotypes through lineage-specific microenvironment sensing

Despite the general focus on an invasive and de-differentiated phenotype as main driver of cancer metastasis, in melanoma patients many metastatic lesions display a high degree of pigmentation, indicative for a differentiated phenotype. Indeed, studies in mice and fish show that melanoma cells switc...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Miskolczi, Zsofia, Smith, Michael P., Rowling, Emily J., Ferguson, Jennifer, Barriuso, Jorge, Wellbrock, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992128/
https://ncbi.nlm.nih.gov/pubmed/29545604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0209-0
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