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Glucose availability controls ATF4-mediated MITF suppression to drive melanoma cell growth
It is well know that cancer cells have adopted an altered metabolism and that glucose is a major source of energy for these cells. In melanoma, enhanced glucose usage is favoured through the hyper-activated MAPK pathway, which suppresses OXPHOS and stimulates glycolysis. However, it has not been add...
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5464841/ https://ncbi.nlm.nih.gov/pubmed/28380427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16514 |
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