A carregar...
Combination of MEK and SRC inhibition suppresses melanoma cell growth and invasion
The RAS-RAF-MEK-ERK pathway is deregulated in over 90% of malignant melanomas and targeting MEK as central kinase of this pathway is currently tested in clinical trials. However, dose-limiting side effects are observed, and MEK inhibitors that sufficiently reduce ERK activation in patients show a lo...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378628/ https://ncbi.nlm.nih.gov/pubmed/22310287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.25 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|