Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload

Pathological cardiac remodeling during heart failure is associated with higher levels of lipid peroxidation products and lower abundance of several aldehyde detoxification enzymes, including aldehyde dehydrogenase 2 (ALDH2). An emerging idea that could explain these findings concerns the role of ele...

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Dades bibliogràfiques
Publicat a:Redox Biol
Autors principals: Dassanayaka, Sujith, Zheng, Yuting, Gibb, Andrew A., Cummins, Timothy D., McNally, Lindsey A., Brittian, Kenneth R., Jagatheesan, Ganapathy, Audam, Timothy N., Long, Bethany W., Brainard, Robert E., Jones, Steven P., Hill, Bradford G.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991908/
https://ncbi.nlm.nih.gov/pubmed/29885625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.05.016
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