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Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload

Pathological cardiac remodeling during heart failure is associated with higher levels of lipid peroxidation products and lower abundance of several aldehyde detoxification enzymes, including aldehyde dehydrogenase 2 (ALDH2). An emerging idea that could explain these findings concerns the role of ele...

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Detalhes bibliográficos
Main Authors: Sujith Dassanayaka, Yuting Zheng, Andrew A. Gibb, Timothy D. Cummins, Lindsey A. McNally, Kenneth R. Brittian, Ganapathy Jagatheesan, Timothy N. Audam, Bethany W. Long, Robert E. Brainard, Steven P. Jones, Bradford G. Hill
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018-07-01
Colecção:Redox Biology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213231718304117
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