Cardiomyocyte Ogt limits ventricular dysfunction in mice following pressure overload without affecting hypertrophy

The myocardial response to pressure overload involves coordination of multiple transcriptional, post-transcriptional, and metabolic cues. The previous studies show that one such metabolic cue, O-GlcNAc, is elevated in the pressure-overloaded heart, and the increase in O-GlcNAcylation is required for...

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Bibliografiska uppgifter
I publikationen:Basic Res Cardiol
Huvudupphovsmän: Dassanayaka, Sujith, Brainard, Robert E., Watson, Lewis J., Long, Bethany W., Brittian, Kenneth R., DeMartino, Angelica M., Aird, Allison L., Gumpert, Anna M., Audam, Timothy N., Kilfoil, Peter J., Muthusamy, Senthilkumar, Hamid, Tariq, Prabhu, Sumanth D., Jones, Steven P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555162/
https://ncbi.nlm.nih.gov/pubmed/28299467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-017-0612-7
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