Cardiomyocyte Ogt limits ventricular dysfunction in mice following pressure overload without affecting hypertrophy

The myocardial response to pressure overload involves coordination of multiple transcriptional, post-transcriptional, and metabolic cues. The previous studies show that one such metabolic cue, O-GlcNAc, is elevated in the pressure-overloaded heart, and the increase in O-GlcNAcylation is required for...

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Detalhes bibliográficos
Publicado no:Basic Res Cardiol
Main Authors: Dassanayaka, Sujith, Brainard, Robert E., Watson, Lewis J., Long, Bethany W., Brittian, Kenneth R., DeMartino, Angelica M., Aird, Allison L., Gumpert, Anna M., Audam, Timothy N., Kilfoil, Peter J., Muthusamy, Senthilkumar, Hamid, Tariq, Prabhu, Sumanth D., Jones, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555162/
https://ncbi.nlm.nih.gov/pubmed/28299467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-017-0612-7
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