Cardiomyocyte Ogt limits ventricular dysfunction in mice following pressure overload without affecting hypertrophy

The myocardial response to pressure overload involves coordination of multiple transcriptional, post-transcriptional, and metabolic cues. The previous studies show that one such metabolic cue, O-GlcNAc, is elevated in the pressure-overloaded heart, and the increase in O-GlcNAcylation is required for...

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Publicado en:Basic Res Cardiol
Main Authors: Dassanayaka, Sujith, Brainard, Robert E., Watson, Lewis J., Long, Bethany W., Brittian, Kenneth R., DeMartino, Angelica M., Aird, Allison L., Gumpert, Anna M., Audam, Timothy N., Kilfoil, Peter J., Muthusamy, Senthilkumar, Hamid, Tariq, Prabhu, Sumanth D., Jones, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555162/
https://ncbi.nlm.nih.gov/pubmed/28299467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-017-0612-7
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