Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload

Pathological cardiac remodeling during heart failure is associated with higher levels of lipid peroxidation products and lower abundance of several aldehyde detoxification enzymes, including aldehyde dehydrogenase 2 (ALDH2). An emerging idea that could explain these findings concerns the role of ele...

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Опубликовано в: :Redox Biol
Главные авторы: Dassanayaka, Sujith, Zheng, Yuting, Gibb, Andrew A., Cummins, Timothy D., McNally, Lindsey A., Brittian, Kenneth R., Jagatheesan, Ganapathy, Audam, Timothy N., Long, Bethany W., Brainard, Robert E., Jones, Steven P., Hill, Bradford G.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2018
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991908/
https://ncbi.nlm.nih.gov/pubmed/29885625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.05.016
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