Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload

Pathological cardiac remodeling during heart failure is associated with higher levels of lipid peroxidation products and lower abundance of several aldehyde detoxification enzymes, including aldehyde dehydrogenase 2 (ALDH2). An emerging idea that could explain these findings concerns the role of ele...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Dassanayaka, Sujith, Zheng, Yuting, Gibb, Andrew A., Cummins, Timothy D., McNally, Lindsey A., Brittian, Kenneth R., Jagatheesan, Ganapathy, Audam, Timothy N., Long, Bethany W., Brainard, Robert E., Jones, Steven P., Hill, Bradford G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991908/
https://ncbi.nlm.nih.gov/pubmed/29885625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.05.016
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