Utrophin haploinsufficiency does not worsen the functional performance, resistance to eccentric contractions and force production of dystrophic mice

The lack of dystrophin in Duchenne muscular dystrophy (DMD) compromises the integrity and function of muscle fibers. Skeletal muscles, except the diaphragm, do not undergo progressive degeneration in adult mdx mice due to compensatory mechanisms, including structural protein upregulation. New mouse...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Boulanger Piette, Antoine, Hamoudi, Dounia, Marcadet, Laetitia, Kyomi Labelle, Frédérique, Ovidiu David, Rares, Bossé, Sabrina, Argaw, Anteneh, Frenette, Jérôme
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991729/
https://ncbi.nlm.nih.gov/pubmed/29879154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198408
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