Haploinsufficiency of Utrophin Gene Worsens Skeletal Muscle Inflammation and Fibrosis in mdx Mice

To address whether mdx mice with haploinsufficiency of utrophin (mdx/utrn+/-) develop more severe skeletal muscle inflammation and fibrosis than mdx mice, to represent a better model for Duchenne muscular dystrophy (DMD), we performed qualitative and quantitative analysis of skeletal muscle inflamma...

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Autores principales: Zhou, Lan, Rafael-Fortney, Jill A., Huang, Ping, Zhao, Xinyu S., Cheng, Georgiana, Zhou, Xiaohua, Kaminski, Henry J., Liu, Liping, Ransohoff, Richard M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696235/
https://ncbi.nlm.nih.gov/pubmed/17889902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2007.08.029
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