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Imatinib attenuates skeletal muscle dystrophy in mdx mice

Duchenne-Meryon muscular dystrophy (DMD) is the most common and lethal genetic muscle disease. Ameliorating muscle necrosis, inflammation, and fibrosis represents an important therapeutic approach for DMD. Imatinib, an antineoplastic agent, demonstrated antiinflammatory and antifibrotic effects in l...

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Detalhes bibliográficos
Main Authors: Huang, Ping, Zhao, Xinyu S., Fields, Matthew, Ransohoff, Richard M., Zhou, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717779/
https://ncbi.nlm.nih.gov/pubmed/19289603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-129833
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