Imatinib attenuates skeletal muscle dystrophy in mdx mice

Duchenne-Meryon muscular dystrophy (DMD) is the most common and lethal genetic muscle disease. Ameliorating muscle necrosis, inflammation, and fibrosis represents an important therapeutic approach for DMD. Imatinib, an antineoplastic agent, demonstrated antiinflammatory and antifibrotic effects in l...

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Bibliografiske detaljer
Main Authors: Huang, Ping, Zhao, Xinyu S., Fields, Matthew, Ransohoff, Richard M., Zhou, Lan
Format: Artigo
Sprog:Inglês
Udgivet: The Federation of American Societies for Experimental Biology 2009
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717779/
https://ncbi.nlm.nih.gov/pubmed/19289603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-129833
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