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CCR2 deficiency does not provide sustained improvement of muscular dystrophy in mdx(5cv) mice

Genetic ablation or pharmacologic inhibition of CC chemokine receptor type 2 (CCR2) reduced macrophage (MP) infiltration and improved muscle pathology and function in mdx diaphragm muscle at early stages. We addressed whether CCR2 deficiency resulted in sustained improvement of mdx(5cv)-Ccr2(−/−) di...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Zhao, Wanming, Wang, Xingyu, Ransohoff, Richard M., Zhou, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161528/
https://ncbi.nlm.nih.gov/pubmed/27655900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600619R
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