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Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle
BACKGROUND: Duchenne muscular dystrophy (DMD) is a lethal X-linked muscle wasting disorder caused by the absence of dystrophin, a large cytoskeletal muscle protein. Increasing the levels of the dystrophin-related-protein utrophin is a highly promising therapy for DMD and has been shown to improve pa...
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| Publicado no: | Skelet Muscle |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5655821/ https://ncbi.nlm.nih.gov/pubmed/29065908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-017-0139-5 |
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