Á lódáil...

Transthyretin Mimetics as Anti-β-Amyloid Agents: A Comparison of Peptide and Protein Approaches

β-Amyloid (Aβ) aggregation is causally linked to neuronal pathology in Alzheimer’s disease; therefore, several small molecules, antibodies, and peptides have been tested as anti-Aβ agents. We developed two compounds based on the Aβ-binding domain of transthyretin (TTR): a cyclic peptide cG8 and an e...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:ChemMedChem
Main Authors: Pate, Kayla M., Kim, Brandon J., Shusta, Eric V., Murphy, Regina M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991081/
https://ncbi.nlm.nih.gov/pubmed/29512286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800031
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!