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Recent evidence that TADs and chromatin loops are dynamic structures

Mammalian genomes are folded into spatial domains, which regulate gene expression by modulating enhancer-promoter contacts. Here, we review recent studies on the structure and function of Topologically Associating Domains (TADs) and chromatin loops. We discuss how loop extrusion models can explain T...

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Detaylı Bibliyografya
Yayımlandı:Nucleus
Asıl Yazarlar: Hansen, Anders S., Cattoglio, Claudia, Darzacq, Xavier, Tjian, Robert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990973/
https://ncbi.nlm.nih.gov/pubmed/29077530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2017.1389365
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