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LC3 Immunostaining in the Inferior Olivary Nuclei of Cats With Niemann-Pick Disease Type C1 Is Associated With Patterned Purkinje Cell Loss

The feline model of Niemann-Pick disease, type C1 (NPC1) recapitulates the clinical, neuropathological, and biochemical abnormalities present in children with NPC1. The hallmarks of disease are the lysosomal storage of unesterified cholesterol and multiple sphingolipids in neurons, and the spatial a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neuropathol Exp Neurol
Prif Awduron: Gurda, Brittney L, Bagel, Jessica H, Fisher, Samantha J, Schultz, Mark L, Lieberman, Andrew P, Hand, Peter, Vite, Charles H, Swain, Gary P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989620/
https://ncbi.nlm.nih.gov/pubmed/29346563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlx119
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