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Conditional Niemann-Pick C mice demonstrate cell autonomous Purkinje cell neurodegeneration
Pathways regulating neuronal vulnerability are poorly understood, yet are central to identifying therapeutic targets for degenerative neurological diseases. Here, we characterize mechanisms underlying neurodegeneration in Niemann-Pick type C (NPC) disease, a lysosomal storage disorder characterized...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2816612/ https://ncbi.nlm.nih.gov/pubmed/20007718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp552 |
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