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The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography
The effect of a mutation on the organism often depends on what other mutations are already present in its genome. Geneticists refer to such mutational interactions as epistasis. Pairwise epistatic effects have been recognized for over a century, and their evolutionary implications have received theo...
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| Published in: | J Stat Phys |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer US
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986866/ https://ncbi.nlm.nih.gov/pubmed/29904213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10955-018-1975-3 |
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