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The Rank Ordering of Genotypic Fitness Values Predicts Genetic Constraint on Natural Selection on Landscapes Lacking Sign Epistasis

Sewall Wright's genotypic fitness landscape makes explicit one mechanism by which epistasis for fitness can constrain evolution by natural selection. Wright distinguished between landscapes possessing multiple fitness peaks and those with only a single peak and emphasized that the former class...

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Autor principal: Weinreich, Daniel M.
Format: Artigo
Idioma:Inglês
Publicat: Copyright © 2005 by the Genetics Society of America 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456840/
https://ncbi.nlm.nih.gov/pubmed/16079241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.036830
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