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The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography

The effect of a mutation on the organism often depends on what other mutations are already present in its genome. Geneticists refer to such mutational interactions as epistasis. Pairwise epistatic effects have been recognized for over a century, and their evolutionary implications have received theo...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Stat Phys
Main Authors: Weinreich, Daniel M., Lan, Yinghong, Jaffe, Jacob, Heckendorn, Robert B.
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer US 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986866/
https://ncbi.nlm.nih.gov/pubmed/29904213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10955-018-1975-3
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