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Should evolutionary geneticists worry about higher-order epistasis?

Natural selection drives evolving populations up the fitness landscape, the projection from nucleotide sequence space to organismal reproductive success. While it has long been appreciated that topographic complexities on fitness landscapes can arise only as a consequence of epistatic interactions b...

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Detalhes bibliográficos
Publicado no:Curr Opin Genet Dev
Main Authors: Weinreich, Daniel M, Lan, Yinghong, Wylie, C Scott, Heckendorn, Robert B
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313208/
https://ncbi.nlm.nih.gov/pubmed/24290990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2013.10.007
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