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One-step, stereoselective synthesis of octahydrochromanes via the Prins reaction and their cannabinoid activities
Novel, functionalized octahydrochromene derivatives were synthesized in a single step via the Prins reaction. Enantiomerically pure (+)-isopulegol was reacted with benzaldehyde to stereoselectively yield the corresponding octahydro-2H-chromen-4-ol derivative containing five stereocenters. A total of...
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| Publicado no: | Tetrahedron Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986293/ https://ncbi.nlm.nih.gov/pubmed/29880989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2018.01.040 |
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