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Isoform selectivity of harmine-conjugated 1,2,3-triazoles against human monoamine oxidase
AIM: There is little information available on the monoamine oxidase isoform selectivity of N-alkyl harmine analogs, which exhibit a myriad of activities including MAO-A, DYRK1A and cytotoxicity to several select cancer cell lines. RESULTS: Compounds 3e and 4c exhibited an IC(50) of 0.83 ± 0.03 and 0...
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| 出版年: | Future Med Chem |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Future Science Ltd
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6021913/ https://ncbi.nlm.nih.gov/pubmed/29788780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0006 |
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