Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody

Pathways of human epidermal growth factor (EGF) receptors are activated upon ligand-dependent or -independent homo- or heterodimerization and their subsequent transphosphorylation. Overexpression of these receptors positively correlates with transphosphorylation rates and increased tumor growth rate...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Oganesyan, Vaheh, Peng, Li, Bee, Jared S., Li, John, Perry, Samuel R., Comer, Frank, Xu, Linda, Cook, Kimberly, Senthil, Kannaki, Clarke, Lori, Rosenthal, Kim, Gao, Changshou, Damschroder, Melissa, Wu, Herren, Dall'Acqua, William
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2018
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986207/
https://ncbi.nlm.nih.gov/pubmed/29669810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.818013
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk