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Molecular basis for antagonistic activity of anifrolumab, an anti-interferon–α receptor 1 antibody

Anifrolumab (anifrolumab) is an antagonist human monoclonal antibody that targets interferon α receptor 1 (IFNAR1). Anifrolumab has been developed to treat autoimmune diseases and is currently in clinical trials. To decipher the molecular basis of its mechanism of action, we engaged in multiple epit...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:MAbs
Päätekijät: Peng, Li, Oganesyan, Vaheh, Wu, Herren, Dall’Acqua, William F, Damschroder, Melissa M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622752/
https://ncbi.nlm.nih.gov/pubmed/25606664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1007810
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