Molecular basis for antagonistic activity of anifrolumab, an anti-interferon–α receptor 1 antibody

Anifrolumab (anifrolumab) is an antagonist human monoclonal antibody that targets interferon α receptor 1 (IFNAR1). Anifrolumab has been developed to treat autoimmune diseases and is currently in clinical trials. To decipher the molecular basis of its mechanism of action, we engaged in multiple epit...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:MAbs
Main Authors: Peng, Li, Oganesyan, Vaheh, Wu, Herren, Dall’Acqua, William F, Damschroder, Melissa M
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2015
Ábhair:
Reports
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622752/
https://ncbi.nlm.nih.gov/pubmed/25606664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1007810
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla