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Molecular basis for the mechanism of action of an anti-TACE antibody
Inhibitors of tumor necrosis factor-α converting enzyme (TACE) have potential as therapeutics for various diseases. Many small molecule inhibitors, however, exhibit poor specificity profiles because they target the highly conserved catalytic cleft of TACE. We report for the first time the molecular...
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| Published in: | MAbs |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098442/ https://ncbi.nlm.nih.gov/pubmed/27610476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1226716 |
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