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A disconnect between precursor frequency, expansion potential, and site-specific CD4(+) T cell responses in aged mice
T cell recognition of peptides presented within self-major histocompatibility complex (pMHC) molecules is essential for long-lived protective immunity. As mice age the number of naïve CD4(+) and CD8(+) T cells declines. However, unlike for CD8(+) T cells, there are more naïve and memory phenotype CD...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986155/ https://ncbi.nlm.nih.gov/pubmed/29864157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198354 |
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