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Age-Related Changes in CD8 T Cell Homeostasis and Immunity to Infection

Studies of CD8 T cell responses to vaccination or infection with various pathogens in both animal models and human subjects have revealed a markedly consistent array of age-related defects. In general, recent work shows that aged CD8 T cell responses are decreased in magnitude, and show poor differe...

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Detalhes bibliográficos
Main Authors: Nikolich-Zugich, Janko, Li, Gang, Uhrlaub, Jennifer L., Renkema, Kristin R., Smithey, Megan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480557/
https://ncbi.nlm.nih.gov/pubmed/22554418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2012.04.009
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