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The aging immune system reveals the biological impact of direct antigen presentation on CD8 T cell responses

The vertebrate immune system employs multiple, sometimes redundant, mechanisms to contain pathogenic microorganisms that are always evolving to evade host defenses. Thus, the cowpox virus (CPXV) uses genes encoding CPXV12 and CPXV203 to prevent direct MHCI presentation of viral peptides by infected...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Uhrlaub, Jennifer L., Smithey, Megan J., Nikolich-Žugich, Janko
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520673/
https://ncbi.nlm.nih.gov/pubmed/28615415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700625
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