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The aging immune system reveals the biological impact of direct antigen presentation on CD8 T cell responses

The vertebrate immune system employs multiple, sometimes redundant, mechanisms to contain pathogenic microorganisms that are always evolving to evade host defenses. Thus, the cowpox virus (CPXV) uses genes encoding CPXV12 and CPXV203 to prevent direct MHCI presentation of viral peptides by infected...

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Bibliographic Details
Published in:J Immunol
Main Authors: Uhrlaub, Jennifer L., Smithey, Megan J., Nikolich-Žugich, Janko
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520673/
https://ncbi.nlm.nih.gov/pubmed/28615415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700625
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