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The aging immune system reveals the biological impact of direct antigen presentation on CD8 T cell responses

The vertebrate immune system employs multiple, sometimes redundant, mechanisms to contain pathogenic microorganisms that are always evolving to evade host defenses. Thus, the cowpox virus (CPXV) uses genes encoding CPXV12 and CPXV203 to prevent direct MHCI presentation of viral peptides by infected...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Uhrlaub, Jennifer L., Smithey, Megan J., Nikolich-Žugich, Janko
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520673/
https://ncbi.nlm.nih.gov/pubmed/28615415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700625
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