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Life-long persistent viral infection alters the naïve T-cell pool, impairing CD8 T-cell immunity in late life()

Persistent CMV infection has been associated with immune senescence. To address the causal impact of life-long persistent viral infection on immune homeostasis and defense, we infected young mice systemically with HSV-1, MCMV or both viruses, and studied their T-cell homeostasis and function. Herpes...

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Detaylı Bibliyografya
Asıl Yazarlar: Smithey, Megan J., Li, Gang, Venturi, Vanessa, Davenport, Miles P., Nikolich-Zugich, Janko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504138/
https://ncbi.nlm.nih.gov/pubmed/23087407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201867
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