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Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections

A diverse and well-balanced repertoire of T cells is thought to be crucial for the efficacious defence against infection with new or re-emerging pathogens throughout life. In the last third of the mammalian lifespan, the maintenance of a balanced T-cell repertoire becomes highly challenging because...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Rev Immunol
Egile nagusia: Nikolich-Žugich, Janko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573867/
https://ncbi.nlm.nih.gov/pubmed/18469829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri2318
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