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West Nile virus-specific CD4 T cells exhibit direct anti-viral cytokine secretion and cytotoxicity and are sufficient for antiviral protection

CD4 T cells have been shown to be necessary for the prevention of encephalitis during West Nile virus infection. However, the mechanisms used by antigen-specific CD4 T cells to protect mice from West Nile virus encephalitis remain incompletely understood. Contrary to the belief that CD4 T cells are...

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Detalhes bibliográficos
Main Authors: Brien, James D., Uhrlaub, Jennifer L., Nikolich-Zugich, Janko
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504655/
https://ncbi.nlm.nih.gov/pubmed/19050276
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