West Nile Virus Capsid Degradation of Claudin Proteins Disrupts Epithelial Barrier Function

During acute infection, West Nile virus (WNV) has been reported to infect a variety of cell types in various tissues of both experimentally and naturally infected hosts. Virus infects epithelial cells in the skin, kidney, intestine, and testes, although the importance of these findings is unclear. I...

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Detalhes bibliográficos
Main Authors: Medigeshi, Guruprasad R., Hirsch, Alec J., Brien, James D., Uhrlaub, Jennifer L., Mason, Peter W., Wiley, Clayton, Nikolich-Zugich, Janko, Nelson, Jay A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687390/
https://ncbi.nlm.nih.gov/pubmed/19369347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02617-08
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