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West Nile Virus Infection Activates the Unfolded Protein Response, Leading to CHOP Induction and Apoptosis
West Nile virus (WNV)-mediated neuronal death is a hallmark of WNV meningitis and encephalitis. However, the mechanisms of WNV-induced neuronal damage are not well understood. We investigated WNV neuropathogenesis by using human neuroblastoma cells and primary rat hippocampal neurons. We observed th...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2045561/ https://ncbi.nlm.nih.gov/pubmed/17686866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01151-07 |
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